Portal:Medicine

The Medicine Portal

The color fresco Care of The Sick by Domenico di Bartolo, 1441–1442, depicting the Santa Maria della Scala hospital in Siena, Italy

Medicine is the science and practice of caring for patients, managing the diagnosis, prognosis, prevention, treatment, palliation of their injury or disease, and promoting their health. Medicine encompasses a variety of health care practices evolved to maintain and restore health by the prevention and treatment of illness. Contemporary medicine applies biomedical sciences, biomedical research, genetics, and medical technology to diagnose, treat, and prevent injury and disease, typically through pharmaceuticals or surgery, but also through therapies as diverse as psychotherapy, external splints and traction, medical devices, biologics, and ionizing radiation, amongst others.

Medicine has been practiced since prehistoric times, and for most of this time it was an art (an area of creativity and skill), frequently having connections to the religious and philosophical beliefs of local culture. For example, a medicine man would apply herbs and say prayers for healing, or an ancient philosopher and physician would apply bloodletting according to the theories of humorism. In recent centuries, since the advent of modern science, most medicine has become a combination of art and science (both basic and applied, under the umbrella of medical science). For example, while stitching technique for sutures is an art learned through practice, knowledge of what happens at the cellular and molecular level in the tissues being stitched arises through science.

Prescientific forms of medicine, now known as traditional medicine or folk medicine, remain commonly used in the absence of scientific medicine and are thus called alternative medicine. Alternative treatments outside of scientific medicine with ethical, safety and efficacy concerns are termed quackery. (Full article...)

Featured articles -

Featured articles are displayed here, which represent some of the best content on English Wikipedia.

---

• 
  
  

  

  The four primary symptoms of ME/CFS according to the National Institute for Health and Care Excellence

  
  Myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) is a disabling chronic illness. People with ME/CFS experience profound fatigue that does not go away with rest, as well as sleep issues and problems with memory or concentration. The hallmark symptom is post-exertional malaise, a worsening of the illness which starts hours to days after minor physical or mental activity. This "crash" can last from hours or days to several months. Further common symptoms include dizziness or faintness when upright and pain.
  
  
  The cause of the disease is unknown. ME/CFS often starts after an infection, such as mononucleosis. It can run in families, but no genes that contribute to ME/CFS have been confirmed. ME/CFS is associated with changes in the nervous and immune systems, as well as in energy production. Diagnosis is based on symptoms and a differential diagnosis because no diagnostic test is available. (Full article...)
• 
  
  

  

  Microscopic image of a Lewy body (adjacent to arrowhead) in a neuron of the substantia nigra; scale bar=20 microns (0.02 mm)

  
  Dementia with Lewy bodies (DLB) is a type of dementia characterized by changes in sleep, behavior, cognition, movement, and regulation of automatic bodily functions. Memory loss is not always an early symptom. The disease worsens over time and is usually diagnosed when cognitive impairment interferes with normal daily functioning. Together with Parkinson's disease dementia, DLB is one of the two Lewy body dementias. It is a common form of dementia, but the prevalence is not known accurately and many diagnoses are missed. The disease was first described on autopsy by Kenji Kosaka in 1976, and he named the condition several years later.
  
  REM sleep behavior disorder (RBD)—in which people lose the muscle paralysis (atonia) that normally occurs during REM sleep and act out their dreams—is a core feature. RBD may appear years or decades before other symptoms. Other core features are visual hallucinations, marked fluctuations in attention or alertness, and parkinsonism (slowness of movement, trouble walking, or rigidity). A presumptive diagnosis can be made if several disease features or biomarkers are present; the diagnostic workup may include blood tests, neuropsychological tests, imaging, and sleep studies. A definitive diagnosis usually requires an autopsy. (Full article...)
• 
  
  

  

  White in 1989

  
  Ryan Wayne White (December 6, 1971 – April 8, 1990) was an American teenager from Kokomo, Indiana, who became a national poster child for HIV/AIDS in the United States after his school barred him from attending classes following a diagnosis of AIDS.
  
  As a hemophiliac, White became infected with HIV from a contaminated factor VIII blood treatment and, when diagnosed in December 1984, was given six months to live. Doctors said he posed no risk to other students, as AIDS is not an airborne disease and spreads solely through bodily fluids, but AIDS was poorly understood by the general public at the time. When White tried to return to school, irate parents and teachers in Howard County rallied against his attendance due to unwarranted concerns of the disease spreading to other students and staff. A lengthy administrative appeal process ensued, and news of the conflict turned White into a popular celebrity and advocate for AIDS research and public education. Surprising his doctors, White lived five years longer than predicted. He died on April 8, 1990, one month before his high school graduation. (Full article...)
• 
  Genetics is the study of genes, genetic variation, and heredity in organisms. It is an important branch in biology because heredity is vital to organisms' evolution. Gregor Mendel, a Moravian Augustinian friar working in the 19th century in Brno, was the first to study genetics scientifically. Mendel studied "trait inheritance", patterns in the way traits are handed down from parents to offspring over time. He observed that organisms (pea plants) inherit traits by way of discrete "units of inheritance". This term, still used today, is a somewhat ambiguous definition of what is referred to as a gene.
  
  Trait inheritance and molecular inheritance mechanisms of genes are still primary principles of genetics in the 21st century, but modern genetics has expanded to study the function and behavior of genes. Gene structure and function, variation, and distribution are studied within the context of the cell, the organism (e.g. dominance), and within the context of a population. Genetics has given rise to a number of subfields, including molecular genetics, epigenetics, and population genetics. Organisms studied within the broad field span the domains of life (archaea, bacteria, and eukarya). (Full article...)
• 
  Ray Fletcher Farquharson MBE (4 August 1897 – 1 June 1965) was a Canadian medical doctor, university professor, and medical researcher. Born in Claude, Ontario, he attended and taught at the University of Toronto for most of his life, and was trained and employed at Toronto General Hospital. With co-researcher Arthur Squires, Farquharson was responsible for the discovery of the Farquharson phenomenon, an important principle of endocrinology, which is that administering external hormones suppresses the natural production of that hormone.
  
  He served in the First and Second World Wars, earning appointment as a Member of the Order of the British Empire for his medical work during the latter. He chaired the Penicillin Committee of Canada and served as a medical consultant for the Royal Canadian Air Force. He was awarded the Queen's Coronation Medal in 1953 for his work for the Defence Review Board. Farquharson was also a charter member of the Royal College of Physicians and Surgeons of Canada. (Full article...)
• 
  
  

  

  A CBC specimen in front of a printout displaying CBC and differential results

  
  A complete blood count (CBC), also known as a full blood count (FBC), is a set of medical laboratory tests that provide information about the cells in a person's blood. The CBC indicates the counts of white blood cells, red blood cells and platelets, the concentration of hemoglobin, and the hematocrit (the volume percentage of red blood cells). The red blood cell indices, which indicate the average size and hemoglobin content of red blood cells, are also reported, and a white blood cell differential, which counts the different types of white blood cells, may be included.
  
  The CBC is often carried out as part of a medical assessment and can be used to monitor health or diagnose diseases. The results are interpreted by comparing them to reference ranges, which vary with sex and age. Conditions like anemia and thrombocytopenia are defined by abnormal complete blood count results. The red blood cell indices can provide information about the cause of a person's anemia such as iron deficiency and vitamin B12 deficiency, and the results of the white blood cell differential can help to diagnose viral, bacterial and parasitic infections and blood disorders like leukemia. Not all results falling outside of the reference range require medical intervention. (Full article...)
• 
  
  

  

  Urine from a person with rhabdomyolysis showing the characteristic brown discoloration as a result of myoglobinuria

  
  Rhabdomyolysis (shortened as rhabdo) is a condition in which damaged skeletal muscle breaks down rapidly, often due to high intensity exercise over a short period. Symptoms may include muscle pains, weakness, vomiting, and confusion. There may be tea-colored urine or an irregular heartbeat. Some of the muscle breakdown products, such as the protein myoglobin, are harmful to the kidneys and can cause acute kidney injury.
  
  
  The muscle damage is most usually caused by a crush injury, strenuous exercise, medications, or a substance use disorder. Other causes include infections, electrical injury, heat stroke, prolonged immobilization, lack of blood flow to a limb, or snake bites as well as intense or prolonged exercise, particularly in hot conditions. Statins (prescription drugs to lower cholesterol) are considered a small risk. Some people have inherited muscle conditions that increase the risk of rhabdomyolysis. The diagnosis is supported by a urine test strip which is positive for "blood" but the urine contains no red blood cells when examined with a microscope. Blood tests show a creatine kinase activity greater than 1000 U/L, with severe disease being above 5000–15000 U/L. (Full article...)
• 
  
  

  

  A large flap lesion in the femur head typical of late stage Osteochondritis dissecans. In this case, the lesion was caused by avascular necrosis of the bone just under the cartilage.

  
  Osteochondritis dissecans (OCD or OD) is a joint disorder primarily of the subchondral bone in which cracks form in the articular cartilage and the underlying subchondral bone. OCD usually causes pain during and after sports. In later stages of the disorder there will be swelling of the affected joint that catches and locks during movement. Physical examination in the early stages does only show pain as symptom, in later stages there could be an effusion, tenderness, and a crackling sound with joint movement.
  
  
  OCD is caused by blood deprivation of the secondary physes around the bone core of the femoral condyle. This happens to the epiphyseal vessels under the influence of repetitive overloading of the joint during running and jumping sports. During growth such chondronecrotic areas grow into the subchondral bone. There it will show as bone defect area under articular cartilage. The bone will then possibly heal to the surrounding condylar bone in 50% of the cases. Or it will develop into a pseudarthrosis between condylar bone core and osteochondritis flake leaving the articular cartilage it supports prone to damage. The damage is executed by ongoing sport overload. The result is fragmentation (dissection) of both cartilage and bone, and the free movement of these bone and cartilage fragments within the joint space, causing pain, blockage and further damage. OCD has a typical anamnesis with pain during and after sports without any history of trauma. Some symptoms of late stages of osteochondritis dissecans are found with other diseases like rheumatoid disease of children and meniscal ruptures. The disease can be confirmed by X-rays, computed tomography (CT) or magnetic resonance imaging (MRI) scans. (Full article...)
• 
  
  

  

  Scanning electron micrograph of Escherichia coli rods

  
  Bacteria (/bækˈtɪəriə/ ; sg.: bacterium) are ubiquitous, mostly free-living organisms often consisting of one biological cell. They constitute a large domain of prokaryotic microorganisms. Typically a few micrometres in length, bacteria were among the first life forms to appear on Earth, and are present in most of its habitats. Bacteria inhabit the air, soil, water, acidic hot springs, radioactive waste, and the deep biosphere of Earth's crust. Bacteria play a vital role in many stages of the nutrient cycle by recycling nutrients and the fixation of nitrogen from the atmosphere. The nutrient cycle includes the decomposition of dead bodies; bacteria are responsible for the putrefaction stage in this process. In the biological communities surrounding hydrothermal vents and cold seeps, extremophile bacteria provide the nutrients needed to sustain life by converting dissolved compounds, such as hydrogen sulphide and methane, to energy. Bacteria also live in mutualistic, commensal and parasitic relationships with plants and animals. Most bacteria have not been characterised and there are many species that cannot be grown in the laboratory. The study of bacteria is known as bacteriology, a branch of microbiology.
  
  Like all animals, humans carry vast numbers (approximately 10¹³ to 10¹⁴) of bacteria. Most are in the gut, though there are many on the skin. Most of the bacteria in and on the body are harmless or rendered so by the protective effects of the immune system, and many are beneficial, particularly the ones in the gut. However, several species of bacteria are pathogenic and cause infectious diseases, including cholera, syphilis, anthrax, leprosy, tuberculosis, tetanus and bubonic plague. The most common fatal bacterial diseases are respiratory infections. Antibiotics are used to treat bacterial infections and are also used in farming, making antibiotic resistance a growing problem. Bacteria are important in sewage treatment and the breakdown of oil spills, the production of cheese and yogurt through fermentation, the recovery of gold, palladium, copper and other metals in the mining sector (biomining, bioleaching), as well as in biotechnology, and the manufacture of antibiotics and other chemicals. (Full article...)
• 
  
  

  

  A serpin (white) with its 'reactive centre loop' (blue) bound to a protease (grey). Once the protease attempts catalysis it will be irreversibly inhibited. (PDB: 1K9O​)

  
  Serpins are a superfamily of proteins with similar structures that were first identified for their protease inhibition activity and are found in all kingdoms of life. The acronym serpin was originally coined because the first serpins to be identified act on chymotrypsin-like serine proteases (serine protease inhibitors). They are notable for their unusual mechanism of action, in which they irreversibly inhibit their target protease by undergoing a large conformational change to disrupt the target's active site. This contrasts with the more common competitive mechanism for protease inhibitors that bind to and block access to the protease active site.
  
  Protease inhibition by serpins controls an array of biological processes, including coagulation and inflammation, and consequently these proteins are the target of medical research. Their unique conformational change also makes them of interest to the structural biology and protein folding research communities. The conformational-change mechanism confers certain advantages, but it also has drawbacks: serpins are vulnerable to mutations that can result in serpinopathies such as protein misfolding and the formation of inactive long-chain polymers. Serpin polymerisation not only reduces the amount of active inhibitor, but also leads to accumulation of the polymers, causing cell death and organ failure. (Full article...)
• 
  
  

  

  Sadler c. 1915

  
  William Samuel Sadler (June 24, 1875 – April 26, 1969) was an American surgeon, self-trained psychiatrist, and author who helped publish The Urantia Book. The book is said to have resulted from Sadler's relationship with a man through whom he believed celestial beings spoke at night. It drew a following of people who studied its teachings.
  
  A native of Indiana, Sadler moved to Michigan as a teenager to work at the Battle Creek Sanitarium. There he met the physician and health-food promoter John Harvey Kellogg, co-inventor of corn flakes breakfast cereal, who became his mentor. Sadler married Kellogg's niece, Lena Celestia Kellogg, in 1897. He worked for several Christian organizations and attended medical school, graduating in 1906. Sadler practiced medicine in Chicago with his wife, who was also a physician. He joined several medical associations and taught at the McCormick Theological Seminary. Although he was a committed member of the Seventh-day Adventist Church for almost twenty years, he left the denomination after it disfellowshipped his wife's uncle, John Harvey Kellogg, in 1907. Sadler and his wife became speakers on the Chautauqua adult education circuit in 1907, and he became a highly paid, popular orator. He eventually wrote over 40 books on a variety of medical and spiritual topics advocating a holistic approach to health. Sadler extolled the value of prayer and religion but was skeptical of mediums, assisting debunker Howard Thurston, and embraced the scientific consensus on evolution. (Full article...)
• 
  
  

  

  Holmes, c. 1879

  
  Oliver Wendell Holmes Sr. (/hoʊmz/; August 29, 1809 – October 7, 1894) was an American physician, poet, and polymath based in Boston. Grouped among the fireside poets, he was acclaimed by his peers as one of the best writers of the day. His most famous prose works are the "Breakfast-Table" series, which began with The Autocrat of the Breakfast-Table (1858). He was also an important medical reformer. In addition to his work as an author and poet, Holmes also served as a physician, professor, lecturer, and inventor.
  
  Born in Cambridge, Massachusetts, Holmes was educated at Phillips Academy and Harvard College. After graduating from Harvard in 1829, he briefly studied law before turning to the medical profession. He began writing poetry at an early age; one of his most famous works, "Old Ironsides", was published in 1830 and was influential in the eventual preservation of the USS Constitution. Following training at the prestigious medical schools of Paris, Holmes was granted his Doctor of Medicine degree from Harvard Medical School in 1836. He taught at Dartmouth Medical School before returning to teach at Harvard and, for a time, served as dean there. During his long professorship, he became an advocate for various medical reforms and notably posited the controversial idea that doctors were capable of carrying puerperal fever from patient to patient. Holmes retired from Harvard in 1882 and continued writing poetry, novels and essays until his death in 1894. (Full article...)
• 
  
  

  

  Sorrowing Old Man (At Eternity's Gate), an 1890 portrait by Vincent van Gogh

  
  Major depressive disorder (MDD), also known as clinical depression, is a mental disorder characterized by at least two weeks of pervasive low mood, low self-esteem, and loss of interest or pleasure in normally enjoyable activities. Introduced by a group of US clinicians in the mid-1970s, the term was adopted by the American Psychiatric Association for this symptom cluster under mood disorders in the 1980 version of the Diagnostic and Statistical Manual of Mental Disorders (DSM-III), and has become widely used since. The disorder causes the second-most years lived with disability, after lower back pain.
  
  The diagnosis of major depressive disorder is based on the person's reported experiences, behavior reported by relatives or friends, and a mental status examination. There is no laboratory test for the disorder, but testing may be done to rule out physical conditions that can cause similar symptoms. The most common time of onset is in a person's 20s, with females affected about twice as often as males. The course of the disorder varies widely, from one episode lasting months to a lifelong disorder with recurrent major depressive episodes. (Full article...)
• 
  Xenon is a chemical element; it has symbol Xe and atomic number 54. It is a dense, colorless, odorless noble gas found in Earth's atmosphere in trace amounts. Although generally unreactive, it can undergo a few chemical reactions such as the formation of xenon hexafluoroplatinate, the first noble gas compound to be synthesized.
  
  Xenon is used in flash lamps and arc lamps, and as a general anesthetic. The first excimer laser design used a xenon dimer molecule (Xe₂) as the lasing medium, and the earliest laser designs used xenon flash lamps as pumps. Xenon is also used to search for hypothetical weakly interacting massive particles and as a propellant for ion thrusters in spacecraft. (Full article...)
• 
  
  

  

  A D. medinensis worm emerges from a wound on a person's foot

  
  Dracunculiasis, also called Guinea-worm disease, is a parasitic infection by the Guinea worm, Dracunculus medinensis. A person becomes infected by drinking water contaminated with Guinea-worm larvae that reside inside copepods (a type of small crustacean). Stomach acid digests the copepod and releases the Guinea worm, which penetrates the digestive tract and escapes into the body. Around a year later, the adult female migrates to an exit site – usually the lower leg – and induces an intensely painful blister on the skin. Eventually, the blister bursts, creating a painful wound from which the worm gradually emerges over several weeks. The wound remains painful throughout the worm's emergence, disabling the affected person for the three to ten weeks it takes the worm to emerge.
  
  There is no medication to treat or prevent dracunculiasis. Instead, the mainstay of treatment is the careful wrapping of the emerging worm around a small stick or gauze to encourage and speed up its exit. Each day, a few more centimeters of the worm emerge, and the stick is turned to maintain gentle tension. Too much tension can break and kill the worm in the wound, causing severe pain and swelling. Dracunculiasis is a disease of extreme poverty, occurring in places with poor access to clean drinking water. Prevention efforts center on filtering drinking water to remove copepods, as well as public education campaigns to discourage people from soaking affected limbs in sources of drinking water, as this allows the worms to spread their larvae. (Full article...)

Selected image –

Diagram of a myocardial infarction

Photo credit: User:JHeuser

WikiProject

Get involved by joining WikiProject Medicine. We discuss collaborations and all manner of issues on our talk page.

Related portals

Good articles -

These are Good articles, which meet a core set of high editorial standards.

---

• 
  
  

  

  Portrait by Max Büttinghausen, 1895–1905

  
  Aletta Henriëtte Jacobs (Dutch pronunciation: [aːˈlɛtaː ɦɑ̃ːriˈjɛtə ˈjaːkɔps]; 9 February 1854 – 10 August 1929) was a Dutch physician and women's suffrage activist. As the first woman officially to attend a Dutch university, she became one of the first female physicians in the Netherlands. In 1882, she founded the world's first birth control clinic and was a leader in both the Dutch and international women's movements. She led campaigns aimed at deregulating prostitution, improving women's working conditions, promoting peace and calling for women's right to vote.
  
  Born in the mid-nineteenth century, Jacobs yearned to become a doctor like her father. Despite existing barriers, she fought to gain entry to higher education and graduated in 1879 with the first doctorate in medicine earned by a woman in the Netherlands. Providing medical services to women and children, she grew concerned over the health of working women, recognizing that as laws did not provide adequate protection for their health, their economic stability was compromised. She opened a free clinic to educate poor women about hygiene and child care and in 1882 expanded her services to include distribution of contraception information and devices. Though she continued to practice medicine until 1903, Jacobs increasingly turned her attention to activism with a view to improving women's lives. (Full article...)
• 
  
  

  

  "Thou hell o' a' diseases" – William Hole's illustration for Robert Burns' poem "Address to the Toothache" (1897, poem c. 1786).

  
  Toothaches, also known as dental pain or tooth pain, is pain in the teeth or their supporting structures, caused by dental diseases or pain referred to the teeth by non-dental diseases. When severe it may impact sleep, eating, and other daily activities.
  
  
  Common causes include inflammation of the pulp, (usually in response to tooth decay, dental trauma, or other factors), dentin hypersensitivity, apical periodontitis (inflammation of the periodontal ligament and alveolar bone around the root apex), dental abscesses (localized collections of pus), alveolar osteitis ("dry socket", a possible complication of tooth extraction), acute necrotizing ulcerative gingivitis (a gum infection), and temporomandibular disorder. (Full article...)
• 

  

  Health workers protest near Salmaniya Medical Complex following reports that paramedic crews and doctors were attacked in the 17 February raid at Pearl Roundabout.

  
  The Bahrain health worker trials were a series of legal cases in which forty-eight doctors, nurses, and dentists faced charges for their actions during the Bahraini uprising of 2011. In September 2011, twenty of the health workers were convicted by a military court of felonies including "stockpiling weapons" and "plotting to overthrow the government". The remaining twenty-eight were charged with misdemeanors and tried separately. The following month, the felony sentences were overturned, and it was announced that the defendants would be retried by a civilian court. Retrials began in March 2012, but were postponed until June 14. Convictions against nine of the defendants were quashed and reduced against another nine. The Court of Cassation upheld the sentences against the remaining nine on 1 October.
  
  The case drew international attention and criticism, with organizations including the United Nations, the World Medical Association, Médecins Sans Frontières, the International Council of Nurses, Amnesty International, and Human Rights Watch expressing their concern over the health workers' military trials and sentences. An independent commission organized by the King of Bahrain concluded in November 2011 that many of the detained health workers had been subject to torture and abuse while in police detention. (Full article...)
• 
  Ann Bishop (19 December 1899 – 7 May 1990) was a British biologist from Girton College at the University of Cambridge and a Fellow of the Royal Society, one of the few female Fellows of the Royal Society. She was born in Manchester but stayed at Cambridge for the vast majority of her professional life. Her specialties were protozoology and parasitology; early work with ciliate parasites, including the one responsible for blackhead disease in the domesticated turkey, lay the groundwork for her later research. While working towards her doctorate, Bishop studied parasitic amoebae and examined potential chemotherapies for the treatment of amoebic diseases including amoebic dysentery.
  
  Her best known work was a comprehensive study of Plasmodium, the malaria parasite, and investigation of various chemotherapies for the disease. Later she studied drug resistance in this parasite, research that proved valuable to the British military in World War II. She discovered the potential for cross-resistance in these parasites during that same period. Bishop also discovered the protozoan Pseudotrichomonas keilini and worked with Aedes aegypti, a malaria vector, as part of her research on the disease. Elected to the Royal Society in 1959, Bishop was the founder of the British Society for Parasitology and served on the World Health Organization's Malaria Committee. (Full article...)
• 

  

  European fur traders doing business with Native Americans in 1777, with a barrel of rum to the left

  
  Many Native Americans in the United States have been harmed by, or become addicted to, drinking alcohol. Among contemporary Native Americans and Alaska Natives, 11.7% of all deaths are related to alcohol. By comparison, about 5.9% of global deaths are attributable to alcohol consumption. Because of negative stereotypes and biases based on race and social class, generalizations and myths abound around the topic of Native American alcohol misuse.
  
  A survey of death certificates from 2006 to 2010 showed that deaths among Native Americans due to alcohol are about four times as common as in the general U.S. population. They are often due to traffic collisions and liver disease, with homicide, suicide, and falls also contributing. Deaths related to alcohol among Native Americans are more common in men and among Northern Plains Indians. Alaska Natives showed the lowest incidence of alcohol-related death. Alcohol misuse amongst Native Americans has been shown to be associated with development of disease, including hearing and vision problems, kidney and bladder problems, head injuries, pneumonia, tuberculosis, dental problems, liver problems, and pancreatitis. In some tribes, the rate of fetal alcohol spectrum disorder is as high as 1.5 to 2.5 per 1,000 live births, more than seven times the national average, while among Alaska Natives, the rate of fetal alcohol spectrum disorder is 5.6 per 1,000 live births. (Full article...)
• 
  Charles DeWitt Watts (September 21, 1917 – July 12, 2004) was an African-American surgeon and activist for the poor. Watts was the first surgeon of African-American ancestry in North Carolina. Earning his medical degree in 1943 from Howard University College, he was the first African-American board-certified surgeon to serve in North Carolina. After surgical training at Freedman's Hospital in Washington, D.C., in 1949, he moved to Durham, North Carolina, in 1950 and established a clinic to provide access to medical services for the poor. Breaking the social customs of racial obstacles, he advocated for certification of African-American medical students. He also became a member of many professional colleges including the National Academy of Science's Institute of Medicine and the American College of Surgeons. He served as chief of surgery at Durham's Lincoln Hospital and was later one of the key figures in converting it to the Lincoln Community Health Center, a low-priced clinic for the poor. (Full article...)
• 
  
  

  

  Karyotype of pentasomy X

  
  Pentasomy X, also known as 49,XXXXX, is a chromosomal disorder in which a female has five, rather than two, copies of the X chromosome. Pentasomy X is associated with short stature, intellectual disability, characteristic facial features, heart defects, skeletal anomalies, and pubertal and reproductive abnormalities. The condition is exceptionally rare, with an estimated prevalence between 1 in 85,000 and 1 in 250,000.
  
  The condition has a large variety of symptoms, and it is difficult to paint a conclusive portrait of its phenotypes. Though significant disability is characteristic, there are so few diagnosed cases that confident conclusions about the presentation and prognosis remain impossible. Pentasomy X may be mistaken for more common chromosomal disorders, such as Down syndrome or Turner syndrome, before a conclusive diagnosis is reached. (Full article...)
• 

  

  
  Warfarin, sold under the brand name Coumadin among others, is an anticoagulant medication. While the drug is described as a "blood thinner", it does not reduce viscosity but rather prevents blood clots (thrombus) from forming (coagulating). Accordingly, it is commonly used to prevent deep vein thrombosis and pulmonary embolism, and to protect against stroke in people who have atrial fibrillation, valvular heart disease, or artificial heart valves. Warfarin may sometimes be prescribed following ST-segment elevation myocardial infarctions (STEMI) and orthopedic surgery. It is usually taken by mouth, but may also be administered intravenously. It is a vitamin K antagonist.
  
  
  The common side effect, a natural consequence of reduced clotting, is bleeding. Less common side effects may include areas of tissue damage, and purple toes syndrome. Use is not recommended during pregnancy. The effects of warfarin are typically monitored by checking prothrombin time (INR) every one to four weeks. Many other medications and dietary factors can interact with warfarin, either increasing or decreasing its effectiveness. The effects of warfarin may be reversed with phytomenadione (vitamin K₁), fresh frozen plasma, or prothrombin complex concentrate. (Full article...)
• 
  The ovulatory shift hypothesis holds that women experience evolutionarily adaptive changes in subconscious thoughts and behaviors related to mating during different parts of the ovulatory cycle. It suggests that what women want, in terms of men, changes throughout the menstrual cycle. Two meta-analyses published in 2014 reached opposing conclusions on whether the existing evidence was robust enough to support the prediction that women's mate preferences change across the cycle. A newer 2018 review does not show women changing the type of men they desire at different times in their fertility cycle. (Full article...)
• 
  
  

  

  Schematic representation of normal ECG trace (sinus rhythm), with waves, segments, and intervals labeled

  
  Short QT syndrome (SQT) is a very rare genetic disease of the electrical system of the heart, and is associated with an increased risk of abnormal heart rhythms and sudden cardiac death. The syndrome gets its name from a characteristic feature seen on an electrocardiogram (ECG) – a shortening of the QT interval. It is caused by mutations in genes encoding ion channels that shorten the cardiac action potential, and appears to be inherited in an autosomal dominant pattern. The condition is diagnosed using a 12-lead ECG. Short QT syndrome can be treated using an implantable cardioverter-defibrillator or medications including quinidine. Short QT syndrome was first described in 2000, and the first genetic mutation associated with the condition was identified in 2004. (Full article...)
• 
  
  

  

  The human karyotype with chromosome 17 highlighted

  
  17q12 microdeletion syndrome, also known as 17q12 deletion syndrome, is a rare chromosomal anomaly caused by the deletion of a small amount of material from a region in the long arm of chromosome 17. It is typified by deletion of the HNF1B gene, resulting in kidney abnormalities and renal cysts and diabetes syndrome. It also has neurocognitive effects, and has been implicated as a genetic factor for autism and schizophrenia.
  
  17q12 microdeletion syndrome is not to be confused with 17q12 microduplication syndrome, caused by the addition of genetic material in the same region from which it is removed in the microdeletion, or 17q21.31 microdeletion syndrome, another name for Koolen–De Vries syndrome. (Full article...)
• 
  
  

  

  Woman during a migraine attack

  
  Migraine (UK: /ˈmiːɡreɪn/, US: /ˈmaɪ-/) is a genetically-influenced complex neurological disorder characterized by episodes of moderate-to-severe headache, most often unilateral and generally associated with nausea and light and sound sensitivity. Other characterizing symptoms may include vomiting, cognitive dysfunction, allodynia, and dizziness. Exacerbation or worsening of headache symptoms during physical activity is another distinguishing feature.
  
  Up to one-third of people with migraine experience aura, a premonitory period of sensory disturbance widely accepted to be caused by cortical spreading depression at the onset of a migraine attack. Although primarily considered to be a headache disorder, migraine is highly heterogenous in its clinical presentation and is better thought of as a spectrum disease rather than a distinct clinical entity. Disease burden can range from episodic discrete attacks to chronic disease. (Full article...)
• 
  
  

  

  A child with smallpox in Bangladesh in 1973. The bumps filled with thick fluid and a depression or dimple in the center are characteristic.

  
  Smallpox was an infectious disease caused by variola virus (often called smallpox virus), which belongs to the genus Orthopoxvirus. The last naturally occurring case was diagnosed in October 1977, and the World Health Organization (WHO) certified the global eradication of the disease in 1980, making smallpox the only human disease to have been eradicated to date.
  
  The initial symptoms of the disease included fever and vomiting. This was followed by formation of ulcers in the mouth and a skin rash. Over a number of days, the skin rash turned into the characteristic fluid-filled blisters with a dent in the center. The bumps then scabbed over and fell off, leaving scars. The disease was transmitted from one person to another primarily through prolonged face-to-face contact with an infected person or rarely via contaminated objects. Prevention was achieved mainly through the smallpox vaccine. Once the disease had developed, certain antiviral medications could potentially have helped, but such medications did not become available until after the disease was eradicated. The risk of death was about 30%, with higher rates among babies. Often, those who survived had extensive scarring of their skin, and some were left blind. (Full article...)
• 
  
  

  

  Facial features generally include a long face with a broad forehead, an open mouth appearance, arched eyebrows, and protruding ears.

  
  Beck–Fahrner syndrome, also known as BEFAHRS and TET3 deficiency, is a rare genetic disorder caused by mutations of the TET3 gene. The clinical presentation varies among individuals, but typically includes global developmental delay, slow progress in mental and physical activities, autism, decreased muscle tone, epilepsy and dysmorphic features.
  
  Mutations in the TET3 gene disrupt DNA demethylation during embryogenesis, an essential epigenetic process contributing to the early development of the nervous system. They can occur from new genetic mutations or be inherited in an autosomal dominant manner. Diagnosis involves molecular and genetic testing in the context of typical symptoms. Management is supportive, aimed at improving quality of life. As of 2023, approximately 50 individuals have been diagnosed with Beck–Fahrner syndrome. (Full article...)
• 

  

  Launch of the Coalition for Epidemic Preparedness Innovations, CEPI in 2017 at the World Economic Forum in Davos, Switzerland.

  
  
  The Coalition for Epidemic Preparedness Innovations (CEPI) is a foundation that takes donations from public, private, philanthropic, and civil society organisations, to finance independent research projects to develop vaccines against emerging infectious diseases (EID).
  
  CEPI is focused on the World Health Organization's (WHO) "blueprint priority diseases", which include: the Middle East respiratory syndrome-related coronavirus (MERS-CoV), the Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the Nipah virus, the Lassa fever virus, and the Rift Valley fever virus, as well as the Chikungunya virus and the hypothetical, unknown pathogen "Disease X". CEPI investment also requires "equitable access" to the vaccines during outbreaks, although subsequent CEPI policy changes may have compromised this criterion. In 2022, CEPI adopted a vision for the world to be able to respond to a pandemic threat with a new vaccine within 100 days. (Full article...)

Did you know –

• ... that one third of the world's current population has tuberculosis (see map shown on the right), and new infections occur at a rate of one per second?
• ... that shortness of breath that is worse when sitting up is called platypnea, which is a sign of hepatopulmonary syndrome?
• ... that obesity increases the risk of cardiovascular diseases, diabetes mellitus type 2, sleep apnea, certain types of cancer, and osteoarthritis, and shortens life expectancy?

General images –

The following are images from various Medicine-related articles on Wikipedia.

• 
  Emil Kraepelin (1856–1926), the founder of modern scientific psychiatry, psychopharmacology and psychiatric genetics (from History of medicine)
• 
  Hippocrates (c. 460–370 BCE). Known as the "father of medicine". (from History of medicine)
• 
  "More Doctors Smoke Camels than Any Other Cigarette" advertisement for Camel cigarettes in the 1940s (from Medical ethics)
• 
  Seven named physicians and botanists of the Classical world from Vienna Dioscurides. Clockwise from top center: Galen, Dioscorides, Nicander, Rufus of Ephesus, Andreas of Carystus, Apollonius Mus or of Pergamon, Crateuas (from History of medicine)
• 
  Galen (129–216 CE), known for his wide insights into anatomy (from History of medicine)
• 
  Replica of Antonie van Leeuwenhoek's microscope of the 1670s (from History of medicine)
• 
  Infographic showing how healthcare data flows within the billing process (from Medical billing)
• 
  Most countries have seen a tremendous increase in life expectancy since 1945. However, in southern Africa, the HIV epidemic beginning around 1990 has eroded national health. (from History of medicine)
• 
  Charite in Berlin (from History of medicine)
• 
  A Ukrainian monument to the HIV pandemic (from History of medicine)
• 
  Medicine during the First World War - medical transport (from History of medicine)
• 
  American Civil War hospital at Gettysburg, 1863 (from History of medicine)
• 
  Health expenditure funding types (from Health insurance)
• 
  Sometimes traditional medicines include parts of endangered species, such as the slow loris in Southeast Asia. (from Traditional medicine)
• 
  "Diagram of the causes of mortality in the army in the East" by Florence Nightingale (from History of medicine)
• 
  A 12th-century manuscript of the Hippocratic Oath in Greek, one of the most famous aspects of classical medicine that carried into later eras (from History of medicine)
• 
  Patient, Surrey County Lunatic Asylum, c. 1850–58. The asylum population in England and Wales rose from 1,027 in 1827 to 74,004 in 1900. (from History of medicine)
• 
  AMA Code of Medical Ethics (from Medical ethics)
• 
  A cuneiform terracotta tablet describing a medicinal recipe for poisoning (c. 18th century BCE). Discovered in Nippur, Iraq.
• 
  Global concentrations of health care resources, as depicted by the number of physicians per 10,000 individuals, by country. Data is sourced from a World Health Statistics 2010, a WHO report. (from Health care)
• 
  Ethical prayer for medical wisdom by Dr Edmond Fernandes (from Medical ethics)
• 
  The Edwin Smith Surgical Papyrus, written in the 17th century BCE, contains the earliest recorded reference to the brain. New York Academy of Medicine. (from History of medicine)
• 
  Medical personnel place sterilized covers on the arms of the daVinci Xi surgical system, a minimally-invasive robotic surgery system, at the William Beaumont Army Medical Center. (from History of medicine)
• 
  Smallpox vaccination in Niger, 1969. A decade later, this was the first infectious disease to be eradicated. (from History of medicine)
• 
  Louis Pasteur experimenting on bacteria, c. 1870 (from History of medicine)
• 
  A 12th-century Byzantine manuscript of the Hippocratic Oath (from Medical ethics)
• 
  The plinthios brochos as described by Greek physician Heraklas, a sling for binding a fractured jaw. These writings were preserved in one of Oribasius' collections. (from History of medicine)
• 
  COVID-19 swab testing in Rwanda (2021) (from History of medicine)
• 
  Botánicas such as this one in Jamaica Plain, Boston, cater to the Latino community and sell folk medicine alongside statues of saints, candles decorated with prayers, lucky bamboo, and other items. (from Traditional medicine)
• 
  Magical stela or cippus of Horus inscribed with healing encantations (c. 332 to 280 BCE) (from History of medicine)
• 
  Sketch of Muslim physician Muhammad ibn Zakariya al-Razi (from History of medicine)
• 
  Mandrake (written 'ΜΑΝΔΡΑΓΟΡΑ' in Greek capitals). Naples Dioscurides, 7th century (from History of medicine)
• 
  American combat surgery during the Pacific War, 1943 (from History of medicine)
• 
  Statue of Robert Koch, father of medical bacteriology, at Robert-Koch-Platz (Robert Koch square) in Berlin (from History of medicine)
• 
  The emergency room is often a frontline venue for the delivery of primary medical care. (from Health care)
• 
  A cochlear implant is a common kind of neural prosthesis, a device replacing part of the human nervous system. (from History of medicine)
• 
  Curandera performing a limpieza in Cuenca, Ecuador (from Traditional medicine)
• 
  18th-century medical remedies collected by a British Gentry family (from History of medicine)
• 
  The Quaker-run York Retreat, founded in 1796, gained international prominence as a centre for moral treatment and a model of asylum reform following the publication of Samuel Tuke's Description of the Retreat (1813). (from History of medicine)
• 
  healthcare expenditure in Japan by age group (from Health insurance)
• 
  Health Expenditure per capita (in PPP-adjusted US$) among several OECD member nations. Data source: OECD's iLibrary (from Health insurance)
• 
  Total healthcare cost per person. Public and private spending. US dollars PPP. For example: $6,319 for Canada in 2022. $12,555 for the US in 2022. (from Health care)
• 
  Depiction of smallpox in Franciscan Bernardino de Sahagún's history of the conquest of Mexico, Book XII of the Florentine Codex, from the defeated Aztecs' point of view (from History of medicine)
• 
  Mexico City epidemic of 1737, with elites calling on the Virgin of Guadalupe (from History of medicine)
• 
  The numbers of Americans lacking health insurance and the uninsured rate from 1987 to 2008 (from Health insurance)
• 
  Jackson Memorial Hospital in Miami, the primary teaching hospital of the University of Miami's Miller School of Medicine and the largest hospital in the United States with 1,547 beds (from Health care)
• 
  Taoist symbol of Yin and Yang (from Medical ethics)
• 
  Life Expectancy of the total population at birth among several OECD member nations. Data source: OECD's iLibrary (from Health insurance)
• 
  Traditional medicine in a market in Antananarivo, Madagascar (from Traditional medicine)
• 
  An American billing clerk preparing a detailed invoice. (1992) (from Medical billing)
• 
  A Neo-Assyrian cuneiform tablet fragment describing medical text (c. 9th to 7th century BCE) (from History of medicine)
• 
  Health spending by country. Percent of GDP (Gross domestic product). For example: 11.2% for Canada in 2022. 16.6% for the United States in 2022. (from Health care)
• 
  Primary care may be provided in community health centers. (from Health care)
• 
  Life expectancy vs healthcare spending of rich OECD countries. US average of $10,447 in 2018. (from Health care)
• 
  Hospital train "Therapist Matvei Mudrov" in Khabarovsk, Russia (from Health care)
• 
  A doctor checks a patient's pulse in Meiji-era Japan. (from History of medicine)
• 
  Guy's Hospital in 1820 (from History of medicine)
• 
  Yarrow, a medicinal plant found in human-occupied caves in the Upper Palaeolithic period (from History of medicine)
• 
  National Hospital for Neurology and Neurosurgery in London, United Kingdom is a specialist neurological hospital. (from Health care)
• 
  Zhang Zhongjing – a Chinese pharmacologist, physician, inventor, and writer of the Eastern Han dynasty (from History of medicine)

More Did you know (auto generated)

• ... that Constance Fozzard was told during her surgical training that women with children could not become consultants?
• ... that fourteenth-century Buddhist monk Tuệ Tĩnh is referred to as a founding father of traditional Vietnamese medicine?
• ... that the Noongar used the Eucalyptus wandoo tree as a medicine and ointment?
• ... that a lack of screening for pregnant women with syphilis in sub-Saharan Africa is associated with increased infant mortality?
• ... that Tang Zonghai was one of the first advocates for the integration of Chinese and Western medicine?
• ... that Mary Robertson was the first woman to receive a Doctor of Science degree in medicine from the University of Cape Town?

Topics

Categories

• Medicine

Category puzzle

Select [►] to view subcategories

Medicine

Medicine by city

Medicine by country

Medicine by country subdivision

Medicine by dependent territory

Medicine by century

Medicine by decade

Medicine by year

Alternative medicine

Clinical medicine

Veterinary medicine

Medical lists

Works about medicine

Medical activism

Medical associations

Medicine awards

Cause (medicine)

Chemicals in medicine

Health-related conspiracy theories

Medical aspects of death

Medical diplomacy

Medical education

History of medicine

Medical humanities

Intersex healthcare

Medical cannibalism

Medical and health organizations

Medical phenomena

Practice of medicine

Prescription of drugs

Medical prevention

Religion and medicine

Medical research

Medicine in society

Medical symbols

Medical technology

Medical terminology

Theory of medicine

Medical volunteerism

Women in medicine

Medicine stubs

• Health
  Clinical research
• Disability
• Diseases and disorders
• Therapy

• Biology
  Anatomy
• Biological engineering
• Bioethics
• Cell biology
• Microbiology
• Physiology

Recognized content

Associated Wikimedia

The following Wikimedia Foundation sister projects provide more on this subject:

• 

  Commons
  Free media repository

• 

  Wikibooks
  Free textbooks and manuals

• 

  Wikidata
  Free knowledge base

• 

  Wikinews
  Free-content news

• 

  Wikiquote
  Collection of quotations

• 

  Wikisource
  Free-content library

• 

  Wikiversity
  Free learning tools

• 

  Wiktionary
  Dictionary and thesaurus

Discover Wikipedia using portals

• 

  List of all portals

• 

  The arts portal

• 

  Biography portal

• 

  Current events portal

• 

  Geography portal

• 

  History portal

• 

  Mathematics portal

• 

  Science portal

• 

  Society portal

• 

  Technology portal

• 

  Random portal

• 

  WikiProject Portals